Kierownik:



prof. dr hab. Zbigniew Figaszewski
e-mail: figaszew@uwb.edu.pl
tel. 085-745-75-96


Pracownicy:

Tematyka prac badawczych:

Bioelektrochemia błon komórkowych i membran sztucznych, w tym gęstość ładunku elektrycznego błony komórkowej, także modele błon komórkowych: napięcie powierzchniowe, impedancja, elektoforeza. Elektrody jonoselektywne z ciekłą membraną. Równowagi kompleksowe w roztworach niewodnych.

Przykładowy zakres prac magisterskich realizowanych w Zakładzie:

1. Potencjometryczne i spektrofotometryczne badanie stałych trwałości związków kompleksowych w roztworach niewodnych.
2. Badanie właściwości elektrycznych dwuwarstwowych membran lipidowych.
3. Wpływ zmian patologicznych oraz wybranych substancji toksycznych na właściwości fizykochemiczne błon komórkowych.
4. Rozdział składników błon komórkowych metodą chromatografii cieczowej.

Publikacje:

1. Brzozowska I., Figaszewski Z. 2003. The influence of pH on Phosphatidylcholine monolayers at the air/aqueous solution interface, Colloid and Surfaces B: Biointerfaces 27: 303-309
2. Brzozowska I., Figaszewski Z. 2002. Interfacial tension of phosphatidylcholine-cholesterol system in monolayers at the air/water interface, Biophysical Chemistry 95: 173-179
3. Petelska A. D., Figaszewski Z. 2002, Interfacial tension of bilayer lipid membrane formed from phosphatidylethanolamine, Biochimica et Biophysica Acta 1567: 79-86
4. Brzozowska I., Figaszewski Z. 2002. The equilibrium of phosphatidylcholine-cholesterol in monolayers at the air/water interface, Colloid and Surfaces B: Biointerfaces 23: 51-58
5. Petelska A. D. , Figaszewski Z. 2002 Effect of pH on the interfacial tension of bilayer lipid membrane formed from phosphatidylcholine or phosphatidylserine, Biochimica et Biophysica Acta 1561:135-146
6. Szachowicz-Petelska B., Dobrzyńska I., Figaszewski Z., Sulkowski S. 2002., Changes in physico-chemical properties of human large intestine tumour cells membrane, Molecular and Cellular Biochemistry 238: 41-47
7. Szachowicz-Petelska B., Figaszewski Z., Lewandowski W., 2001 Mechanisms of transport across cell membranes of complexes contained in antitumour drugs. International Journal of Pharmaceutics 222:169-182
8. Naumowicz M., Wencel A., Figaszewski Z. 2001. Application of alkylated crown ether derivative in modifying selectivity of polypropylene membranes, J. Macromol. Sci.-Pure Appl. Chem., A 38(3): 291-306
9. Skrzydlewska E., Dobrzyńska I., Kasacka I., Figaszewski Z. 2001. Effect of vitamin E derivative (U83836E) on membranes of rat liver cells after methanol intoxication, Polish Journal of Environmental Studies Vol.10, No.2: 95-100
10. Gorodkiewicz E., Figaszewski Z., 2001. Study of the stability of some ion-pairs in non-aqueous solution by potentiometric and spectrophotometric methods, Polish J.Chem.,75:127-133
11. Gorodkiewicz E., Figaszewski Z., 2000. Study of the stability and formation rate of the complex compounds of Ni(II), Cu(II), Hg(II) with PAN by potentiometric and spectrophotometric methods, Chem. Anal. (Warsaw), 45:867
12. Ostrowska J., Skrzydlewska E., Figaszewski Z., 2000, Isolation and analysis of phospholipids, Chem.Anal.(Warsaw), 45:613
13. Dobrzyńska I., Skrzydlewska E., Kasacka I., Figaszewski Z., 2000 Protective effect of N-Acetylocysteine on rat liver cell membrane during methanol intoxication, J. Pharm. Pharmacol., 52:547-552
14. Petelska A. D., Figaszewski Z. 2000. Effect of pH on the interfacial tension of lipid bilayer membrane, Biophysical Journal, vol.78: 812-817
15. Magnuszewska B., Ostrowska J., Figaszewski Z., 2000, Determination of papaverine hydrochloride in injection with an ion-selective electrode, Chem. Anal. 45:105-115
16. Dobrzyńska I., Skrzydlewska E., Figaszewski Z. 1999 Influence of trolox derivative and N-acetylocysteine on surface charge density of erythrocytes in methanol intoxicated rats. Environmental Toxicology and Pharmacology 8:15-21
17. Dobrzyńska I., Skrzydlewska E., Figaszewski Z. 1999 Influence of ethanol on the changes in rat liver cells membrane after methanol intoxication. Polish Journal of Environmental Studies vol. 8, supl. II : 248-251
18. Ostrowska J., Roszkowska A., Skrzydlewska E., Figaszewski Z., 1999, HPLC study of the modification of haemoglobin by formaldehyde. Acta Chromatographica No.9: 87-95
19. Skrzydlewska E., Dobrzyńska I., Figaszewski Z. 1998. Oxidative processes and changes of surface charge density of erythrocytes in rat during methanol intoxication, Cellular & Molecular Biology Letters 2: 345-353.
20. Molisak-Tołwińska H., Wencel A., Figaszewski Z. 1998. The effect of hydrophilization of polypropylene membranes with alcohols on their transport properties, J. Macromol. Sci. - Pure Appl. Chem. A 35: 857-865.
21. Magnuszewska B., Figaszewski Z. 1998. Application of promazine compound with cadmium tetraiodide complex in the liquid membrane of an ion-selective electrode, Chem. Anal. (Warsaw) 43: 265-273.
22. Kalinowski S., Ibron G., Bryl K., Figaszewski Z. 1998. Chronopotentiometric studies of electroporation of bilayer lipid membranes, Biochimica et Biophysica Acta 1369: 204-212.
23. Gorodkiewicz E., Figaszewski Z. 1998. Potentiometric and spectrophotometric measurements of stability constants of complexes in non-aqueous solutions, Chem. Anal. (Warsaw) 43: 445-456.
24. Skrzydlewska E., Ostrowska J., Figaszewski Z., 1998, Peptide mapping by high-performance liquid chromatography, Acta Chromatographica, no. 8: 70-85
25. Petelska A. D. Figaszewski Z., Interfacial tension of two-component bilayer lipid membrane modelling of cell membrane, Bioelectrochemistry and Bioenergetics 46:199-204
26. Molisak-Tołwińska H., Wencel A., Figaszewski Z. 1997. Impedance of polypropylene membranes hydropholized with ethyl alcohol, J. Macromolec. Sci. - Pure Appl. Chem. A34: 1413-1427.
27. Oksiejczuk E., Figaszewski Z., 1997, Electric charge Density of Lung Cancer Cells, CELL MOL BIOL, , Vol. 2, Supl.1
28. Skrzydlewska E., Dobrzyńska I., Figaszewski Z., 1997, Oxidative Processes and Changes of the Surface Charge Density of Erythrocytes in Rat During Methanol Intoxication, Cellular Molecular Biology Letters, Vol.2, pp 345-355
29. Kalinowski S., Figaszewski Z., 1997, The Structural Changes of Bilayer Lipid Membranes Caused by Polarization Potential CELL MOL BIOL, Vol.2, Supl. 1
30. Gorodkiewicz E., Figaszewski Z., 1995, Photodissociation of Thiocyanato Fe(III) Complexes and Hydrazinato Ni(II) Comples, Chem. Anal., Vol 40, 961, pp 961-969